DEVELOPMENT OF A NOVEL NOISE DELIVERY SYSTEM FOR JP-8 OTOTOX IBD

Sinopse

Numerous chemicals with ototoxic properties may cause hearing loss directly, potentiate noise-induced hearing loss, or produce additive effects. Of interest to the US Air Force are studies showing ototoxic effects of JP-8 jet fuel and its hydrocarbon constituents. The Naval Health Research Center (NHRC) at Wright-Patterson AFB, Ohio, in conjunction with the USAF, is studying the ototoxic effects of JP-8 in rats. The study requires a white noise source that is one octave band wide, centered at 8 kHz frequency, delivered from outside of exposure chambers. Sound pressure levels must be within +/- 2 dB at all exposure points within each chamber and within +/- 2 dB over a 6-hour run. Electrodynamic shakers were successfully used to produce the required input noise in three exposure chambers by inducing vibration in chamber plenums. Distribution of sound pressure levels across chamber exposure points were well controlled within a +/- 1.5 dB prediction interval ( = 0.05) or better. Stability at a central reference point was well controlled over 6-hour runs within a +/- 1 dB prediction interval ( = 0.05) or better. The final system solution gives the NHRC a unique capability to deliver noise and whole-body JP-8 aerosol exposures simultaneously.This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.